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Dedicated to increasing awareness about
systemic lupus erythematosus (SLE), disease activity and related organ damage

Quality of Life and SLE

SLE has a considerable impact on patients, including their psychosocial well-being, interpersonal relationships, quality of life, and productivity, which may result in increased healthcare utilization.1-6

A critical component of treating patients with SLE is providing them with reputable, relevant information. Learn more now.

hospitalized patient

Up to 24X

Hospitalizations for serious infections in patients with SLE7,*

Approximately
20%-25%

of patients with SLE are hospitalized annually4,8

hospital

1 in 6

patients are readmitted
within 30 days6

*

Retrospective analysis using data of the Nationwide Inpatient Sample (NIS), Healthcare Cost and Utilization Project, of the Agency for Healthcare Research and Quality from 1996-2011.

Patients with SLE have impaired function affecting multiple aspects of their daily lives. The majority of patients report a periodic or permanent effect on their daily activities.1

In a prospective study of 829 patients with SLE, 91% reported a negative effect on their ability to perform at least one valued life activity, such as cooking, family care, and sleeping.2

Percentage of Patients Who Reported a Negative Effect on Daily Activities

patients daily activities

SLE also impacts patients' career decisions9,*:

Changed their career paths due to the disease9

Retired or quit working earlier than planned9

Reduced their work hours9

*

Data from the 2011 National Burden of Lupus survey funded and developed by GSK. This survey included 957 people in the lupus community — 502 people who reported being diagnosed with SLE, 204 supporters (family members or friends) of people with lupus and 251 rheumatologists.

Survival rates of SLE patients have improved over the past 5 years, but SLE patients still have a 2.6X higher mortality rate compared with the general population.10

PATIENT CASE STUDY: CHRISTA

patient christa

As a mother of two active school-aged children, Christa has had to reduce her involvement in her kids' lives due to her fatigue from SLE.

This is a hypothetical patient.

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PATIENT CASE STUDY: BRIANNE

patient brianne

Brianne is a full-time professional with worsening SLE symptoms that affect her ability to do her day-to-day job.

This is a hypothetical patient.

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LEARN MORE ABOUT SLE

This slide deck discusses the path to diagnosis of SLE, pathogenesis of the disease, impact on patients, and how to best support patients.

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What Next?

SLE affects a wide variety of organ systems, therefore, monitoring for organ damage should be conducted regularly.11,12

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References:
1. Boomsma MM, Bijl M, Stegeman CA, et al. Patients' perceptions of the effects of systemic lupus erythematosus on health, function, income, and interpersonal relationships: a comparison with Wegener's granulomatosis. Arthritis Rheum. 2002;47:196-201. http://dx.doi.org/10.1002/art.10341. Accessed February 14, 2017. 2. Katz P, Morris A, Trupin L, et al. Disability in valued life activities among individuals with systemic lupus erythematosus. Arthritis Rheum. 2008;59(4):465-473. http://dx.doi.org/10.1002/art.23536. Accessed February 14, 2017. 3. Kiani AN, Strand V, Fang H, et al. Predictors of self-reported health-related quality of life in systemic lupus erythematosus. Rheumatology. 2013;52(9):1651-1657. http://dx.doi.org/10.1093/rheumatology/ket171. Accessed February 14, 2017. 4. Panopalis P, Yazdany J, Gillis JZ, et al. Health care costs and costs associated with changes in work productivity among persons with systemic lupus erythematosus. Arthritis Rheum. 2008;59(12):1788-1795. http://dx.doi.org/10.1002/art.24063. Accessed February 14, 2017. 5. Chakravarty EF, Bush TM, Manzi S, et al. Prevalence of adult systemic lupus erythematosus in California and Pennsylvania in 2000: estimates obtained using hospitalization data. Arthritis Rheum. 2007;56(6):2092-2094. http://dx.doi.org/10.1002/art.22641. Accessed February 14, 2017. 6. Yazdany J, Marafino BJ, Dean ML, et al. Thirty-day hospital readmission in systemic lupus erythematosus. Arthritis Rheum. 2014;66(10):2828-2836. http://dx.doi.org/10.1002/art.38768. Accessed February 14, 2017. 7. Tektonidou MG, Wang Z, Ward MM. Burden of Serious Infections in Adults With Systemic Lupus Erythematosus: A National Population-Based Study, 1996-2011. Arthritis Care Res (Hoboken). 2015;67(8):1078-85. http://dx.doi.org/10.1002/acr.22575. Accessed February 14, 2017. 8. Bernatsky S, Boivin JF, Joseph L, et al. Mortality in systemic lupus erythematosus. Arthritis Rheum. 2006;54(8):2550-2557. http://dx.doi.org/10.1002/art.21955. Accessed February 14, 2017. 9. Lupus: A Survey Among SLE Patients, Physicians, and Supporters. New York, NY: GfK Roper Public Affairs & Corporate Communications; October 2011. 10. Lee YH, Choi SJ, Ji JD, Song GG. Overall and cause-specific mortality in systemic lupus erythematosus: an updated meta-analysis. Lupus. January 24, 2016. http://dx.doi.org/10.1177/0961203315627202. Accessed February 14, 2017. 11. American College of Rheumatology Ad Hoc Committee on Systemic Lupus Erythematosus Guidelines. Guidelines for referral and management of systemic lupus erythematosus in adults. Arthritis Rheum. 1999;42(9):1785-1796. http://www.ncbi.nlm.nih.gov/pubmed/10513791. Accessed February 14, 2017. 12. Wallace DJ, Hahn B, eds. Dubois' Lupus Erythematosus. 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007.